Mycobacterium tuberculosis Growth After Aerobic Expression of the DosR Regulon
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE33752
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资源简介：
Investigation of whole genome gene expression of M. tuberculosis strain H37Rv:deltaRv3133c::pEXNF-3133c following ectopic expression of a plasmid-borne copy of wildtype Rv3133c compared the same strain with Rv3133c uninduced. The M. tuberculosis H37Rv:deltaRv3133c was originally described in Mol Microbiol. 2003 May; 48(3): 833–843. A six chip experiment in which total RNA from H37Rv:deltaRv3133c::pEXNF-3133c was collected after 24 hours of treatment with chemical expression inducer or vehicle control. Three separate cultures/biological replicates were interrogated for both induced and uninduced samples. Labeled cDNA was hybridized to NimbleGen spotted oligo tiling arrays covering both strands of the M. tuberculosis genome at ~200 bp intervals between 60-mer probes.
创建时间：
2012-03-23
