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Next Generation Sequencing of Wild Type and Nlrp6-/- T cells

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NIAID Data Ecosystem2026-04-30 收录
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https://www.ncbi.nlm.nih.gov/sra/SRP151659
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Nlrp6 is expressed by T cells, but whether Nlrp6 influences the transcriptom of T cells is not known Methods: Equal numbers of Wild Type and Nlrp6-/- CD4 T cells were adoptively transfered in RAG-/- hosts, isolated from the colonic lamina propria and mRNA profiles gernerated by next generation squencing in quadruplicates using Illumina squencers. Conclusions: Our study indicates that Nlrp6 may regulate genes that are involved in apoptosis of T cells Overall design: Equal numbers of Wild Type and Nlrp6-/- CD4 T cells were adoptively transfered in RAG-/- hosts, isolated from the colonic lamina propria and mRNA profiles gernerated by next generation squencing in quadruplicates using Illumina squencers.
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2021-11-19
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