Essential Role of Sirt2 in Type I Interferon Signaling
收藏NIAID Data Ecosystem2026-03-10 收录
下载链接：
https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE66033
下载链接
链接失效反馈官方服务：
资源简介：
We provide evidence for the essential role of Sirt2 in IFN mediated signaling. Our studies demonstrate that SIRT2 controls expression of key interferon stimulated genes (ISGs) that mediate important biological functions, including anti-viral and antineoplastic responses. Total RNA was isolated from untreated and IFNβ-treated Sirt2+/+ and Sirt2-/- mouse embryonic fibroblasts (MEFs). Cells were treated for 4hours with or without mouse IFNβ (2500 IU/ml).
创建时间：
2019-01-16
