Chrne

ENCODES a protein that exhibits acetylcholine-gated monoatomic cation-selective channel activity; transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential (ortholog); INVOLVED IN monoatomic cation transport; skeletal muscle contraction; regulation of membrane potential (ortholog); PARTICIPATES IN acetylcholine signaling pathway via nicotinic acetylcholine receptor; ASSOCIATED WITH congenital myasthenic syndrome (ortholog); congenital myasthenic syndrome 1A (ortholog); congenital myasthenic syndrome 1B (ortholog); FOUND IN acetylcholine-gated channel complex; neuromuscular junction (ortholog); postsynaptic membrane (ortholog); INTERACTS WITH (+)-schisandrin B; 1-naphthyl isothiocyanate; 17beta-estradiol

编码一种表现出乙酰胆碱门控单原子阳离子选择性通道活性的蛋白质；参与调节突触后膜电位（同源物）的传递门控单原子离子通道活性；涉及单原子阳离子转运；骨骼肌收缩；调节膜电位（同源物）；通过烟碱型乙酰胆碱受体参与乙酰胆碱信号通路；与先天性肌无力综合征（同源物）、先天性肌无力综合征1A（同源物）、先天性肌无力综合征1B（同源物）相关；存在于乙酰胆碱门控通道复合物中；神经肌肉接头（同源物）；突触后膜（同源物）；与（+）-五味子素B、1-萘基异硫氰酸酯、17β-雌二醇相互作用。