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Crystal structure of c-Met in complex with pyrazolone inhibitor 58a

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Protein Data Bank Japan2023-09-13 更新2026-03-21 收录
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Crystal structure of c-Met in complex with pyrazolone inhibitor 58a Descriptor: Hepatocyte growth factor receptor, N-{3-fluoro-4-[(7-methoxyquinolin-4-yl)oxy]phenyl}-1-[(2R)-2-hydroxypropyl]-5-methyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazole-4-carboxamide Authors: Bellon, S.F, Whittington, D.A, Long, A.L. Deposit date: 2011-10-12 Release date: 2012-02-22 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (2.1 Å) Cite: Structure-based design of novel class II c-Met inhibitors: 1. Identification of pyrazolone-based derivatives. J.Med.Chem., 55, 2012

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2011-10-12
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