Cytotoxic analysis of the novel isoflavones, their anti-HIV activity and the time-of-addition studies to quantify the entry inhibiting capabilities of the isoflavones, all in TZM-bl cell

This dataset includes the cytotoxic analysis of the novel isoflavones in TZM-bl cells utilising an MTT assay. The results are the analysed quantified product produced from viable cells. The results were used to determine the concentration of cytotoxicity 50 % (CC50). The anti-HIV studies took place in TZM-bl cells utilising a luciferase reporter assay. The results are the quantified luminescence recorded in the presence of the isoflavones to produce the half maximal inhibitory concentration (IC50). The time-of-addition results utilised the same luciferase reporter assay but with time limitations to quantify the entry-inhibiting capabilities of the novel isoflavones.

本数据集收录了新型异黄酮在TZM-bl细胞中的细胞毒性分析，采用MTT法进行检测。分析结果为从存活细胞中产生的定量产物。结果被用于确定细胞毒性50%（CC50）的浓度。抗HIV研究在TZM-bl细胞中进行，利用荧光素酶报告基因检测法。分析结果为在异黄酮存在下记录的定量荧光，以产生半数抑制浓度（IC50）。时间添加结果使用相同的荧光素酶报告基因检测法，但设定时间限制以量化新型异黄酮的进入抑制能力。