Transcriptome analysis and differentially expressed gene screening for hypoxic-ischemic brain damage in rats treated with acupuncture

Conclusion: we found several significant lncRNAs whose corresponding target genes might be the targets of acupuncture therapy for HIBD. The results of our study may provide new perspectives on the mechanism of acupuncture and affect the diagnosis and therapy of HIBD结论：本研究发现多个具有显著统计学意义的长链非编码RNA（long non-coding RNAs，lncRNAs），其对应的靶基因可作为缺氧缺血性脑损伤（Hypoxic-ischemic brain damage，HIBD）针灸治疗的潜在作用靶点。本研究结果可为阐释针灸治疗的作用机制提供新的研究视角，同时可为缺氧缺血性脑损伤的诊断与治疗带来新的参考方向。