Determining the role of serum progesterone monitoring by comparing endometrial transcriptomics in women with low progesterone versus women with normal progesterone during the receptive phase of the menstrual cycle

Abnormally low progesterone results in an aberrance of endometrial gene expression affecting the chance of implantation. Therefore, serum progesterone monitoring for embryo transfer in the natural cycle is useful and it seems to be potentially applicable for artificial cycles with using similar thresholds. The participants were categorized into two groups based on their progesterone level: normal progesterone (>15 ng/ml) and low progesterone (<15 ng/ml). Global endometrial gene expression between the two groups was compared by microarray technique