It has been widely recognized that the early or delayed puberty appears to display harmful effects on adult health outcomes. During the timing of puberty, pituitaries responds to the hypothalamus and
We investigated the combined effects of H4K16 acylations in vivo using a mouse model of short-chain acyl-CoA dehydrogenase deficiency (SCADD), which causes metabolic challenges and systemic shifts in
Although numerous data have revealed correlations of histone modifications with chromatin activities such as transcription, proofs of their causal importance in gene expression regulation remain limit
The Mediator complex coordinates regulatory input for transcription driven by RNA Polymerase II in eukaryotes. reduced epidermal fluorescence4-3 (ref4-3) is a semidominant mutation that results in a s
