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Synthesis of Enantiomerically Enriched 3‑Amino-2-oxindoles through a Palladium-Mediated Asymmetric Intramolecular Arylation of α‑Ketimino Amides

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Figshare2016-02-20 更新2026-04-29 收录
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https://figshare.com/articles/dataset/Synthesis_of_Enantiomerically_Enriched_3_Amino_2_oxindoles_through_a_Palladium_Mediated_Asymmetric_Intramolecular_Arylation_of_Ketimino_Amides/2484850
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A highly efficient and enantioselective synthesis of 3-amino-2-oxindoles through a palladium-catalyzed asymmetric intramolecular arylation of α-ketimino amides using (R)-DiFluorPhos as the coordinating ligand is reported. This report constitutes the first enantioselective palladium-catalyzed arylation of ketimines.
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2016-02-20
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