Crystal structure of radiolytically cleaved trabectedin-DNA complex

Crystal structure of radiolytically cleaved trabectedin-DNA complex Descriptor: 12-mer double-stranded DNA, [(6aS,7R,13S,14S,15S,16R)-5-(acetyloxy)-8,14-dihydroxy-9-methoxy-4,10,17-trimethyl-6,7,12,13,14,16-hexahydro-2H,6aH-7,13-epimino[1,3]dioxolo[7,8]isoquinolino[3,2-b][3]benzazocin-16-yl]methyl (1R)-6-hydroxy-7-methoxy-1-(sulfanylmethyl)-1,2,3,4-tetrahydroisoquinoline-1-carboxylate Authors: Hou, C, Tsodikov, O.V. Deposit date: 2026-02-16 Release date: 2026-05-27 Last modified: 2026-06-03 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Crystal Structure of Trabectedin-DNA Complex. J.Mol.Biol., 438, 2026