STRUCTURAL CHANGES OF HEPATOCYTES UNDER LONG-TERM STRESS

Scientific approaches have concluded that long-term stress leads to various physiological and metabolic changes in the body and negatively affects multiple organs. Among these organs, the liver is particularly sensitive to stress factors when metabolic processes are altered. Liver plates are composed of hepatocytes, which play a critical role in metabolism, detoxification, and synthesis processes in the body. This article examines how long-term stress causes vacuolization, predisposition to fatty degeneration, and nuclear morphological changes in hepatocytes. Research results demonstrate that prolonged stress negatively impacts the morphological state of liver cells.