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OXTOX: Can Oxaliplatin neurotoxicity be reduced with ibudilast in people with metastatic colorectal cancer – a phase II randomised study

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NIAID Data Ecosystem2026-03-12 收录
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https://www.omicsdi.org/dataset/ecrin-mdr-crc/2469007
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Interventions: Ibudilast 30mg oral twice a day for prevention of acute neurotoxicity for the duration of taking oxaliplatin chemotherapy commencing 2 days prior to starting oxaliplatin. Primary outcome(s): Acute neurotoxicity assessed by the Oxaliplatin Acute Symptom Questionnaire[Day 3 of week 4 for CAPOX and day 3 of week 5 for FOLFOX.] Study Design: Purpose: Prevention; Allocation: Randomised controlled trial; Masking: Blinded (masking used);Assignment: Parallel;Type of endpoint: Safety/efficacy
创建时间:
2021-01-15
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