Crystal structure of human secretory glutaminyl cyclase in complex with (Z)-3-((1H-benzo[d]imidazol-5-yl)methylene)-4-hydroxyindolin-2-one
收藏Protein Data Bank Japan2024-06-26 更新2026-04-19 收录
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Crystal structure of human secretory glutaminyl cyclase in complex with (Z)-3-((1H-benzo[d]imidazol-5-yl)methylene)-4-hydroxyindolin-2-one Descriptor: (3~{Z})-3-(1~{H}-benzimidazol-5-ylmethylidene)-4-oxidanyl-1~{H}-indol-2-one, Glutaminyl-peptide cyclotransferase, ZINC ION Authors: Li, G.-B, Wang, X.-Y. Deposit date: 2023-12-15 Release date: 2024-06-12 Last modified: 2024-06-26 Method: X-RAY DIFFRACTION (2.813 Å) Cite: X-ray Structure-Guided Discovery of a Potent Benzimidazole Glutaminyl Cyclase Inhibitor That Shows Activity in a Parkinson's Disease Mouse Model. J.Med.Chem., 67, 2024
创建时间：
2023-12-15
