Transcriptomic of hrdB regulatory strain in the Streptomyces lividans TK24 secdonary metabolism.

To avoid the complex switches and to reduce the limitations of different metabolic stages on the synthesis of metabolites, we designed a Streptomyces self-sustained system (StSS) that contains two functional modules, the primary metabolism module (PM) and the secondary metabolism module (SM). Here, the transcriptomic of hrdB regulatory strain in the secondary metabolism was analyzed. mRNA profiles of 84 h PM egulatory strain and SM egulatory strain