Genome-wide chromatin structure alteration during Epstein-Barr virus infection (Hi-C)

We analysed chromatin structure alterations by EBV infection to elucidate their contribution to tumorigenesis. We performed Hi-C using gastric epithelial cells with or without EBV infection. Hi-C experiments in 14 Gastric cancer cell lines, 2 normal gastric epithelial cells, a primary EBV(+) gastric cancer tissue, and EBV infected or uninfected gastric cancer cells.