Genome-wide maps of chromatin remodeler binding in acute myeloid leukemia cell line.

We have used chromatin immunoprecipitation followed by high throughput sequencing to map regions of chromatin remodeler binding in Control and KDM6A knock down AML cells. We have used this data to determine KDM6A contribution to chromatin remodeler binding and thus understand its role in leukemogenesis. Binding profile of the core ATP-ase subunit of the NuRD chromatin remodeler in Control and KDM6A knock down AML cell line.