Structure of SARS-CoV-2 3CL protease in complex with the cyclopropane based inhibitor 1c
收藏Protein Data Bank Japan2024-11-20 更新2026-04-04 收录
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Structure of SARS-CoV-2 3CL protease in complex with the cyclopropane based inhibitor 1c Descriptor: 3C-like proteinase, N-{(2S)-1-oxo-3-[(3S)-2-oxopyrrolidin-3-yl]propan-2-yl}-N~2~-({[(1R,2R)-2-phenylcyclopropyl]methoxy}carbonyl)-L-leucinamide Authors: Lovell, S, Kashipathy, M.M, Battaile, K.P, Nguyen, H.N, Chamandi, S.D, Picard, H.R, Madden, T.K, Thruman, H.A, Kim, Y, Groutas, W.C, Chang, K.O. Deposit date: 2022-01-26 Release date: 2022-06-22 Last modified: 2024-11-20 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Broad-Spectrum Cyclopropane-Based Inhibitors of Coronavirus 3C-like Proteases: Biochemical, Structural, and Virological Studies. Acs Pharmacol Transl Sci, 6, 2023
创建时间:
2022-01-26



