Investigation of the properties of conductivity signals in BK channels by Empirical Mode Decomposition

The idea of the project is the comprehensive time-frequency analysis of ion current data registered from BK channels of the different cell lines and measured under the different experimental conditions. Decomposition of signals into individual frequency modes and application of non-linear measures in the form of Information Entropy or Hurst exponent to individual signal components will allow for a more detailed analysis of the information hidden behind the complex ionic conduction sequences. The sample data contains patch-clamp sequences.