Dataset for New-Delhi Metallo-ß-Lactamase: A Global Review for a Global Threat, J. V. Schwarte and K. M. Fromm, Cambridge Scholars Publishing, 2025

New-Delhi metallo-β-lactamase (NDM) is one of the most worrying bacterial resistance markers, due to its worldwide dissemination and its ease to be transferred as gene or protein from resistant to susceptible bacteria. Currently, research focuses around potential inhibitors, some of which display high Ki on the enzyme alone, but display much weaker results against the bacteria or in in vivo tests. To avoid such disappointments, this review covers knowledge from all concerned areas, such as chemistry, microbiology, structural biology, genetics, and pharmacy. It also links the knowledge from these different domains to display a full picture of the current knowledge about NDM. The review highlights thus the evolution of NDM over time, its mechanism of action, its mutations and transfer pathways, as well as the currently known ways to inhibit NDM, just as much as genetic features which caused the anchoring of NDM to the outer membrane, endowing it with the capacities to overcome scarce zinc conditions, more stability, and several other characteristics. To find new tools against NDM, this review aims to gather all information about NDM from any research field, and to explain causes and consequences in a language understandable for all chemists.