Additional file 1: Table S1. of A missense mutation in solute carrier family 12, member 1 (SLC12A1) causes hydrallantois in Japanese Black cattle

Primer information for Y chromosome and GAPDH. Table S2.The shared haplotype of hydrallantois in the affected fetuses. Positions are based on the UMD3.1 assembly of the bovine genome. Table S3.Detailed features of CNVs in the critical region of hydrallantois in 1481 Japanese Black cattle. Positions are based on the UMD3.1 assembly of the bovine genome. CNVs were detected from 1481 Japanese Black cattle [17] using the Illumina BovineHD BeadChip Array [15]. 1 loss type of CNV is the deleted type; gain type of CNV is the duplicated type. 2 Haplotypes of 1481 animals were determined by Beagle software. Table S4.Genes within the critical region of hydrallantois in Japanese Black cattle. Positions are based on the UMD3.1 assembly of the bovine genome. Table S5.Primer information for g.62111230G > A and g.62382825G > A. Positions are based on the UMD3.1 assembly of the bovine genome. Table S6.Transcript and protein ID of bovine SLC12A1. Table S7.Genotypes of two variants validated using Sanger sequencing. 1 Phenotype was diagnosed by veterinarians following the standard guidelines and textbooks (for diagnosis criteria, see [1]). 2 Haplotypes were genotyped by GGP_SuperLDv2-0 26 K BeadChip and determined by Beagle software. 3 N = Non-risk-haplotype; Risk = risk-haplotype. Table S8.Primer information for exon of SLC12A1. Positions are based on the UMD3.1 assembly of the bovine genome. Table S9.Bartter syndrome-associated genes and their positions on the UMD3.1 assembly of the bovine genome. Positions are based on the UMD3.1 assembly of the bovine genome. 1 Bartter syndrome type 4B is caused by simultaneous mutations in both the CLCNKA and CLCNKB genes. 2 CLCNKB is not identified or mapped on the UMD3.1 assembly of the bovine genome. 3 Gitelman syndrome is formerly considered a subset of the Bartter syndrome. (XLSX 50 kb)