Copper(I) Complexes with Trispyrazolylmethane Ligands: Synthesis, Characterization, and Catalytic Activity in Cross-Coupling Reactions
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https://figshare.com/articles/dataset/Copper_I_Complexes_with_Trispyrazolylmethane_Ligands_Synthesis_Characterization_and_Catalytic_Activity_in_Cross_Coupling_Reactions/2499013
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资源简介：
Three novel Cu(I) complexes bearing tris(pyrazolyl)methane
ligands,
Tpmx, have been prepared from reactions of equimolar amounts
of CuI and the ligands Tpm, (HC(pz)3), Tpm*, (HC(3,5-Me2-pz)3), and TpmMs, (HC(3-Ms-pz)3). X-ray diffraction studies have shown that the Tpm and TpmMs derivatives exhibit a 2:1 Cu:ligand ratio, whereas the Tpm*
complex is a mononuclear species in nature. The latter has been employed
as a precatalyst in the arylation of amides and aromatic thiols with
good activity. The synthesis of a Tpm*Cu(I)-phthalimidate, a feasible
intermediate in this catalytic process, has also been performed. Low
temperature 1H NMR studies in CDCl3 have indicated
that this complex exists in solution as a mixture of two, neutral
and ionic forms. Conductivity measurements have reinforced this proposal,
the ionic form predominating in a very polar solvent such as DMSO.
The reaction of Tpm*Cu(I)-phthalimidate with iodobenzene afforded
the expected C–N coupling product in 76% yield accounting for
its role as an intermediate in this transformation.
创建时间：
2012-08-06
