Total number of SNP of sequenced AFB62 or AFB62F9 intermediate (bold) and high level resistant isolates in itraconazole, posaconazole, or voriconazole after in vitro selection.

Number of mutations in relevant genes erg11A, erg25A, hmg1, ssc70, ganA, and the ABC transporter (AFUA_92.m00226) are presented. Strains in bold were selected under intermediate drug concentrations, strain in italics were direct derivatives of strains in bold selected at high drug concentrations. Numbers in parentheses refer to the number of individual SNPs identified in each gene. Details on the specific mutations are found in S4 Table. Itra—itraconazole, Posa—posaconazole, Vori—voriconazole.
Total number of SNP of sequenced AFB62 or AFB62F9 intermediate (bold) and high level resistant isolates in itraconazole, posaconazole, or voriconazole after in vitro selection.