The pharmacokinetic properties of meropenem were investigated in nine critically ill patients treated by continuous venovenous hemofiltration (CVVH). All patients received one dose of 1 g of meropenem
CLva: vancomycin clearance. CLcr: creatinine clearance calculated from serum creatinine with Cockcroft and Gault [11]. Vd: volume of distribution. Mean (±SD) for Age, CLcr, CLva, Vd, Creatinine for pa
The pharmacokinetics of piperacillin-tazobactam were investigated in eight anuric intensive care patients treated by continuous venovenous hemodialysis (CVVHD). The elimination half-life of piperacill
The protocol of a clinical study aimed at the characterization of the pharmacokinetics of piperacillin and tazobactam and its association with the concentrations of inflammatory markers and adrenal st