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PCIF1-mediated deposition of 5-cap N6,2-O-dimethyladenosine in ACE2 and TMPRSS2 mRNA regulates susceptibility to SARS-CoV-2 infection

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NIAID Data Ecosystem2026-03-14 收录
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE208533
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We applied m6Am-exo-seq and RNA-seq on lung cancer to profile the differentially expressed genes and compared the results with m6A-exo-seq To investigate the relationship between gene expression and m6Am modification on transcripts, differentially expressed genes (DEGs) are characterized by RNA-seq, m6Am modified transcripts are detected by m6A-exo-seq. Then DEGs and m6Am modified transcripts are intersected to obtain the genes whose expression are regulated by m6Am RNA modification
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2023-03-10
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