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Enantio- and Diastereoselective Synthesis of Spiro-epoxyoxindoles

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Figshare2016-02-17 更新2026-04-29 收录
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https://figshare.com/articles/dataset/Enantio_and_Diastereoselective_Synthesis_of_Spiro_epoxyoxindoles/2301061
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An asymmetric synthesis of epoxyoxindoles from isatins has been developed by employing chiral sulfur ylides generated in situ from camphor-derived sulfonium salts. This reaction allows an efficient access to enantioenriched spiro-epoxyoxindoles under mild reaction conditions, featuring high yields and excellent enantio- and diastereoselectivities.
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2016-02-17
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