Crystal Structure of the VIM-2 Acquired Metallo-beta-Lactamase in Complex with Taniborbactam (VNRX-5133)
收藏Protein Data Bank Japan2024-01-24 更新2026-03-21 收录
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Crystal Structure of the VIM-2 Acquired Metallo-beta-Lactamase in Complex with Taniborbactam (VNRX-5133) Descriptor: (4~{R})-4-[2-[4-(2-azanylethylamino)cyclohexyl]ethanoylamino]-3,3-bis(oxidanyl)-2-oxa-3-boranuidabicyclo[4.4.0]deca-1(10),6,8-triene-10-carboxylic acid, ACETATE ION, Metallo-beta-lactamase VIM-2, ... Authors: Docquier, J.D, Pozzi, C, De Luca, F, Benvenuti, M, Mangani, S. Deposit date: 2019-08-31 Release date: 2020-01-22 Last modified: 2024-01-24 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Discovery of Taniborbactam (VNRX-5133): A Broad-Spectrum Serine- and Metallo-beta-lactamase Inhibitor for Carbapenem-Resistant Bacterial Infections. J.Med.Chem., 63, 2020
创建时间：
2019-08-31
