Class IA PI3Kinase regulatory subunit p85α regulates mast cell growth and survival related genes

ChEBI2011-09-27 更新2026-07-21 收录

细胞信号调控

肥大细胞功能研究

数据链接：

https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-32410 数据链接链接失效反馈

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资源简介：

Class IA PI3Kinase regulatory subunit p85α regulates mast cell growth and survival related genes

创建时间：

2011-09-27

GIT-PIX蛋白复合物形成相分离调控信号转导的分子机制研究

蛋白相分离

细胞信号调控

信号蛋白复合物（包括酶）在特定的亚细胞区域聚集是细胞信号转导的关键过程。在这一过程中，信号蛋白通过传统热力学原理介导的蛋白-蛋白相互作用被招募到特定的细胞区室高效调节信号转导。近年来研究发现，生物大分子能够通过液-液相分离（liquid-liquid phase separation, LLPS）机制聚集相关信号蛋白，形成无膜区室（membraneless compartment），LLPS提供了

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Data from: Temporal and gefitinib-sensitive regulation of cardiac cytokine expression via chronic β-adrenergic receptor stimulation

心脏分子病理学

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Chronic stimulation of β-adrenergic receptors (βAR) can promote survival signaling via transactivation of epidermal growth factor receptor (EGFR), but ultimately alters cardiac structure and contracti

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The Human Cytomegalovirus UL11 Protein Interacts with the Receptor Tyrosine Phosphatase CD45, Resulting in Functional Paralysis of T Cells

病毒免疫逃逸机制

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Human cytomegalovirus (CMV) exerts diverse and complex effects on the immune system, not all of which have been attributed to viral genes. Acute CMV infection results in transient restrictions in T ce

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LRIG1 is a gatekeeper to exit from quiescence in adult neural stem cells

神经干细胞

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Adult neural stem cells (NSCs) must tightly regulate quiescence and proliferation. Single cell analysis has suggested a continuum of cell states as NSCs exit quiescence. Here we capture and characteri

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T细胞免疫应答

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Interleukin 6 (IL-6) is a pleiotropic cytokine with diverse roles in homeostasis, inflammation, and cancer. Here we performed transcriptional profiling of OT-I CD8+ T cells activated in the presence o

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Class IA PI3Kinase regulatory subunit p85α regulates mast cell growth and survival related genes

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