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Mus musculus strain:C57BL/6 Raw sequence reads. Mus musculus strain:C57BL/6

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NIAID Data Ecosystem2026-05-01 收录
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In this study, we have demonstrated that EPIREG, a CRISPR-derived epigenetic modulation tool, has the capability of eliminating HBV antigens by inhibiting the transcription of cccDNA and integrated DNA through concurrent DNA methylation and histone modification at the promoter region of the HBV genome. Through RNA-seq, WGBs and CUT&Tag sequencing, we assessed the off-target effect of EPIREG

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2024-02-24
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