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Substrate-bound crystal structure of a P450 enzyme DmlH that catalyze intramolecular phenol coupling in the biosynthesis of cihanmycins

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Protein Data Bank Japan2026-08-12 更新2026-08-24 收录
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Substrate-bound crystal structure of a P450 enzyme DmlH that catalyze intramolecular phenol coupling in the biosynthesis of cihanmycins Descriptor: (E)-3-[2-[(2R,3S)-3-[(1R)-1-aminocarbonyloxypropyl]oxiran-2-yl]phenyl]prop-2-enoic acid, Cytochrome P450, PROTOPORPHYRIN IX CONTAINING FE, ... Authors: Fang, C, Zhang, L, Zhu, Y, Zhang, C. Deposit date: 2023-08-30 Release date: 2024-06-12 Last modified: 2026-08-12 Method: X-RAY DIFFRACTION (2.2 Å) Cite: Discovery and Biosynthesis of Cihanmycins Reveal Cytochrome P450-Catalyzed Intramolecular C-O Phenol Coupling Reactions. J.Am.Chem.Soc., 2024

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2023-08-30
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