Equilibrium dissociation constants for the binding of unfractionated heparin by antithrombin variants.
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Dissociation constants (KD) and maximal fluorescence increase were measured by global fitting of fluorescence titrations with unfractionated heparin as described in Materials and Methods section. The differences between mutants were tested for statistical significance by paired t-test, where p-values were <0.005.
Equilibrium dissociation constants for the binding of unfractionated heparin by antithrombin variants.
创建时间：
2014-12-08
