In-vitro heteroresistant MTBC mixtures. BinoSNP
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https://www.ncbi.nlm.nih.gov/bioproject/PRJEB83317
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In-vitro validation As the evaluation with in-silico datasets showed convincing results, we next produced in-vitro datasets by mixing DNAs from M. tuberculosis H37Rv strains carrying single mutations in rpoB (RpoB Ser531Leu and RpoB His526Pro) and wildtype parental M. tuberculosis H37Rv reference strain (ATCC 27294) at different ratios (1:99, 5:95 and 10:90) of mutant/wildtype DNA. NGS data were obtained with an average coverage of 600× and processed.
创建时间：
2024-12-12
