The epigenetics of LBP in NAFLD

NIAID Data Ecosystem2026-05-01 收录

非酒精性脂肪肝表观遗传学

增强子ChIP-seq分析

数据链接：

https://www.ncbi.nlm.nih.gov/sra/SRP474065 数据链接链接失效反馈

官方服务：

资源简介：

We constructed LBP-/- rats with NAFLD and performed integrative analysis of targeting-active enhancer H3K27ac chromatin immunoprecipitation coupled with high-throughput sequencing to explore the potential epigenetic pathomechanisms of active enhancer in the exacerbation of NAFLD upon LBP deficiency.

创建时间：

2023-11-26

Promoter capture Hi-C identifies long-range promoter contact dynamics in response to diet and the development of non-alcoholic fatty liver disease. Promoter capture Hi-C identifies long-range promoter contact dynamics in response to diet and the development of non-alcoholic fatty liver disease

非酒精性脂肪肝表观遗传学

染色质互作

We profiled the chromatin interactions in liver from mice fed either an obesogenic or control diet. Overall design: Examination of chromatin interactions, histone modification, gene expression and tra

NIAID Data Ecosystem30

ChIP-seq of enhancer-associated transcription factors and histone modifications. ChIP-seq of enhancer-associated transcription factors and histone modifications

增强子ChIP-seq分析

转录因子与组蛋白修饰

The datasets presented here are transcription factors, transcriptional co-factors or histone modifications associated with active enhancers in a variety of mouse and human cell types. Overall design:

NIAID Data Ecosystem20

Alterations in the hepatocyte epigenetic landscape in steatosis

非酒精性脂肪肝表观遗传学

细胞甲基化分析

Fatty liver disease or the buildup of fat in the liver, has been reported to affect the global population. This comes with an increased risk for the development of fibrosis, cirrhosis, and hepatocellu

NIAID Data Ecosystem10

DNA IP for 5hmC modified CpGs in the liver of control and HFD fed mouse liver.. DNA IP for 5hmC modified CpGs in the liver of control and HFD fed mouse liver.

非酒精性脂肪肝表观遗传学

5hmC免疫沉淀测序

We carry out 5-hydroxymethylation DNA immunoprecipitation (hmeDIP) prior to sequencing Ion Proton P1 to report on the genome-wide 5hmC patterns of hepatic in murine hepatic steatosis. Overall design:

NIAID Data Ecosystem30

Human liver biopsy of different phases from control to NASH

非酒精性脂肪肝表观遗传学

NAFLD疾病进展分子机制

Non-alcoholic fatty liver disease (NAFLD) is the most common chronic liver disorder in industrialized countries. Liver samples from morbidly obese patients (N=45) with all stages of NAFLD and controls

NIAID Data Ecosystem20

The epigenetics of LBP in NAFLD

资源简介：

相关数据集