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MEK1 with PF-04622664 Bound

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Protein Data Bank Japan2024-02-21 更新2026-03-21 收录
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https://pdbj.org/mine/summary/3dv3
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资源简介:
MEK1 with PF-04622664 Bound Descriptor: 3,4-difluoro-2-[(2-fluoro-4-iodophenyl)amino]-N-(2-hydroxyethoxy)-5-[(2-hydroxyethoxy)methyl]benzamide, ADENOSINE-5'-TRIPHOSPHATE, Dual specificity mitogen-activated protein kinase kinase 1, ... Authors: Kazmirski, S.L, Kothe, M, Ding, Y.-H. Deposit date: 2008-07-18 Release date: 2009-07-21 Last modified: 2024-02-21 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Beyond the MEK-pocket: can current MEK kinase inhibitors be utilized to synthesize novel type III NCKIs? Does the MEK-pocket exist in kinases other than MEK? Bioorg.Med.Chem.Lett., 19, 2009
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2008-07-18
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