A General Organocatalytic Approach toward the Enantioselective Total Synthesis of Indolizidine Based Alkaloids
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https://figshare.com/articles/dataset/A_General_Organocatalytic_Approach_toward_the_Enantioselective_Total_Synthesis_of_Indolizidine_Based_Alkaloids/2462554
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Four indolizidine based alkaloids (IBAs) have been synthesized in a highly enantioselective, straightforward, and flexible manner. As a key step our previously developed Brønsted acid catalyzed vinylogous Mannich reaction was employed which easily afforded gram amounts of an optically pure central intermediate which can be converted into a wide range of diversely substituted IBAs.
创建时间：
2016-02-20
