Overlap between the +1 interactome for the products of genes in the GWAS white+grey zone and those of genes in the +1 interactome of the worm RNAi screen.

The human AD GWAS white+grey zone genes, and their +1 interactors, overlap with the human orthologues of worm-screen hits, and their +1 interactors. Worm screen genes that have human orthologues with a significantly non-random +1 interactome overlap with the GWAS list are shown in bold. Worm screen genes that have human orthologues that interact directly with GWAS genes are marked with an asterisk.