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Regulation of PRDM1 (PRDBF-1/BLIMP1) isoform expression in T cells by an Inflammatory Bowel Disease -associated polymorphism

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NIAID Data Ecosystem2026-05-02 收录
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https://www.ncbi.nlm.nih.gov/sra/SRP077662
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This study aimed to determine if a particular IBD-associated PRDM1 SNP (rs6911490) could be implicated in regulating human CD4+ T cell responses and ultimately IBD pathogenesis. Overall design: Whole genome transcriptome analysis in stimulated CD4+ TE/M cells to compare the transcriptome change between UC patients carrying or lacking the rs6611490 risk allele.
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2025-06-02
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