4See: a flexible browser to explore 4C data

For ease of visual inspection of 4C data we present 4See, a versatile and user-friendly browser. 4See allows 4C profiles from the same bait to be flexibly plotted together, allowing biological replicates to either be compared, or pooled for comparisons between different cell types or experimental conditions. 4C profiles can be integrated with gene tracks, linear epigenomic profiles and annotated regions of interest, such as called significant interactions, allowing rapid data exploration with limited computational resources or bioinformatics expertise. 4C-seq experiment on mouse ES cells before (two baits) and after (one bait) in vitro differentiation, and on CD4+/CD8+ double positive mouse thymocytes (two baits)