Crystal structure of pyruvate dehydrogenase kinase isoform 2 in complex with inhibitor PS35
收藏Protein Data Bank Japan2023-09-27 更新2026-03-21 收录
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Crystal structure of pyruvate dehydrogenase kinase isoform 2 in complex with inhibitor PS35 Descriptor: 4-({5-[(piperidin-4-yl)amino]-1,3-dihydro-2H-isoindol-2-yl}sulfonyl)benzene-1,3-diol, L(+)-TARTARIC ACID, [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, ... Authors: Gui, W.J, Tso, S.C, Chuang, J.L, Wu, C.Y, Qi, X, Wynn, R.M, Chuang, D.T. Deposit date: 2016-04-05 Release date: 2017-01-25 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (1.65 Å) Cite: Development of Dihydroxyphenyl Sulfonylisoindoline Derivatives as Liver-Targeting Pyruvate Dehydrogenase Kinase Inhibitors. J. Med. Chem., 60, 2017
创建时间：
2016-04-05
