Supplementary Tables 1-6

Table S1. Subject characteristics – mutational load measurements in peripheral mononuclear blood cells. Table S2. Data structuring for maternal DESeq2 contrasts. PC1 eigen values for each collection were investigated for significant stratification by covariates using linear models. Covariates with a significant effect on PC1 eigen value stratification were included in DESeq model for respective collection contrasts (columns). P-value 0.1 used to allow for greater sensitivity in DESeq model. Table S3. mtDEGs detected in maternal and fetal tissues. mtDEGs were identified via matching of DEGs to MitoCarta3.0 databases Table S4: Mitochondrial interaction gene sets analyzed by TcGSA. Bold values represent significant gene sets. No gene sets were significant in null-model testing Table S5. References supporting classification of MRPL38 and FKBP8 gene set pathway enrichments under the broader classifications of “Cell death/survival” and “Immune system”.