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Transcriptomic analysis of Mtb H37Rv on treatment with ATD-3169 (Redox generating compound)

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NIAID Data Ecosystem2026-03-10 收录
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE61618
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Mtb H37Rv was found to be highly susceptible to ATD-3169 (Redox generating compound). To further understand the mechanism of ATD-3169 action, we performed microarray analysis of Mtb H37Rv exposed to 3µM, 30 µM and 150µM of ATD-3169 for 4h. Mtb H37Rv was grown till early log phase and treated with ATD-3169 concentrations (3uM, 30uM, 150uM) for 4 hours at 37 degrees at 180rpm. Three independent experiments were done for each of the strain.
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2018-01-08
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