The Landscape of Medicinal Chemistry in Viksit Bharat 2047: Strategic Imperatives for Self-Reliance and Global Leadership in Drug Discovery

As India marches towards its centennial milestone of independence in 2047, the vision of a “Viksit Bharat” (Developed India) necessitates a profound structural evolution from being the “pharmacy of the world” via generic manufacturing to becoming a dominant global epicentre for novel drug discovery. This comprehensive strategic paper analyzes the multi-dimensional scope of medicinal chemistry in India towards 2047. We examine the critical convergence of artificial intelligence (AI-driven de novo drug design), quantum computing, structural biology, and green organic synthesis within the Indian academic and industrial ecosystems. The paper maps out strategic imperatives required to bridge the gap between academic synthetic chemistry and translation into clinical development. Special emphasis is placed on addressing tropical and lifestyle diseases prevalent in the Global South, leveraging India's rich biodiversity through reverse pharmacology, and creating robust Public-Private Partnerships (PPPs). Ultimately, this analysis outlines a roadmap for building a self-reliant, sustainable, and innovation-driven medicinal chemistry infrastructure capable of leading global healthcare paradigms by 2047. KEYWORDS: Viksit Bharat 2047; Medicinal Chemistry; Drug Discovery; Generics to Innovation; AI-Driven Design; Green Synthesis; Self-Reliance.Viksit Bharat 2047