Number of loci and genes gained and lost in a lineage-specific way as well as the number of lineage-specific pseudogenes and proteins with lineage-specific gain or loss of ZNF domains.

H = Human, C = Chimpanzee, O = Orangutan, R = Rhesus macaque, HC = Hominines, HCO = Hominids. Note that we cannot distinguish locus gain in HCO from locus loss in R neither place domain changes on the HCO or R lineage. Numbers in parentheses are rates of changes per Million years (My), assuming a divergence time of humans and chimpanzees of 4.5–6 My, of humans and orangutans of 12–16 My, and of humans and rhesus macaques of 25–33 My.