LAE technical data
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This document describes the input parameters of the LAE antimicrobial compounds that will be used to enhance the conservation of cheese. This table is in connection with the deliverable 3.2. The objective of the deliverable 3.2 was to identify and characterize the active functionalities, namely antimicrobial compounds and oxygen scavengers, and the intelligent functionalities, namely the RFID based biosensor, to be included in packaging in order to improve and control the storage of targeted products packaged with the new PHBV packaging. To achieve the active functionalites objective (regarding antimicrobial compounds), the best anti-microbial molecules were selected depending on their Minimum Inhibitory Concentration (MIC), their Admissible Daily Intake (ADI) and odor threshold value (if any). The quantity to be added in the packaging material was calculated thanks to the modeling. Analysis of the literature and the study of the exposure assessment have permitted to select the LAE for cheese. LAE is a non-volatile molecule. It is intended to migrate into food when intimate contact between packaging and food is achieved. This migration will depend on the diffusivity value of LAE in the polymer matrix and the partition coefficient KPL between polymer and food.The LAE concentration in food should be compared to the MIC value and the admissible dose intake (ADI) to confirm the potential action of LAE as antimicrobial compounds for cheese. This present table is a summary of technical data on LAE used to dimension active based packaging for cheese containing LAE.
本文件详述了用于提升奶酪保鲜效果的月桂酰精氨酸乙酯（LAE）抗菌化合物的输入参数。本表格与交付成果3.2相关。交付成果3.2的目标为识别并表征两类功能组分：其一为活性功能成分，包括抗菌化合物与除氧剂；其二为智能功能成分，即基于射频识别（RFID）的生物传感器，将其纳入包装体系以优化并管控采用新型PHBV包装的目标产品的储存流程。为达成抗菌化合物相关的活性功能成分研发目标，研究人员依据最低抑菌浓度（Minimum Inhibitory Concentration）、每日允许摄入量（Admissible Daily Intake）以及气味阈值（若有）筛选出最优抗菌分子。包装材料中需添加的剂量通过建模计算得出。通过文献调研与暴露评估研究，最终选定LAE应用于奶酪保鲜。LAE为非挥发性分子，当包装与食品实现紧密接触时，其可向食品中迁移。该迁移过程取决于LAE在聚合物基质中的扩散系数，以及聚合物与食品间的分配系数KPL。食品中的LAE浓度需与最低抑菌浓度（MIC）及每日允许摄入量（ADI）进行比对，以验证LAE作为奶酪抗菌化合物的潜在效用。本表格为针对含LAE的奶酪活性包装的尺寸设计所用的LAE技术数据汇总。
