RNA-seq to characterize estrogen receptor alpha mutation in the female rat right ventricle with pressure overload
收藏Alliance of Genome Resources2026-08-01 收录
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Conclusions: ERα in females is protective against RV-pulmonary vascular uncoupling, diastolic dysfunction, and fibrosis in response to pressure overload. ERα appears to be dispensable for RV adaptation in males. ERα may be a mediator of superior RV adaptation in female patients with PAH.
