SARS-CoV-2 Infection of Pluripotent Stem Cell-derived Human Lung Alveolar Type 2 Cells Elicits a Rapid Epithelial-Intrinsic Inflammatory Response. Huang et al
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Transient upregulation of IRF1 during exit from naive pluripotency confers viral protection
Stem cells intrinsically express a subset of genes which are normally associated with interferon stimulation and the innate immune response. However, expression of these interferon stimulated genes (I
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Differential expression of antiviral factors in H9c2 cells overexpressing Cacnb4 of the Cav1.2 channel. Differential expression of antiviral factors in H9c2 cells overexpressing Cacnb4 of the Cav1.2 channel
L-type voltage gated Ca channels play a critical role in E-C coupling in cardiac muscle. alpha1C is associated with beta auxiliary subunits (b1-b4), which regulate cardiac Ca channel gating properties
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Expression of Concern: Reduction in ATP Levels Triggers Immunoproteasome Activation by the 11S (PA28) Regulator during Early Antiviral Response Mediated by IFNβ in Mouse Pancreatic β-Cells
Expression of Concern: Reduction in ATP Levels Triggers Immunoproteasome Activation by the 11S (PA28) Regulator during Early Antiviral Response Mediated by IFNβ in Mouse Pancreatic β-Cells
Figshare2020-02-18 更新30
Macrophages show unprecedented anti-HIV activity in HIV-infected iHMD-NSG mice
Very little is known about the role of macrophages as immune mediators during natural HIV infection. Humanized mice are a highly valuable in vivo model to study HIV pathogenesis. Still, the presence o
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Acid ceramidase of macrophages traps herpes simplex virus in multivesicular bodies and protects from severe disease
Macrophages have important protective functions during infection with herpes simplex virus type 1 (HSV-1). However, molecular mechanisms that restrict viral propagation and protect from severe disease
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