In vivo editing in a mouse PKU model using AAVHSC15 HMI233
收藏NIAID Data Ecosystem2026-03-13 收录
官方服务：
资源简介：
In vivo genome editing of liver PAH in a mouse model of PKU
应用场景：
创建时间：
2022-05-24
相关数据集
mouse gut metagenome Metagenome
We used a metagenomic approach on fecal samples in order to understand if Lb. brevis treatment associated to high-fat diet has a role in modulating or reversing the composition of the gut microbiota i
NIAID Data Ecosystem90
从高脂血症猕猴中分离出的Distasonis副拟杆菌菌株的完整基因组序列Feces_Read和组装统计
使用PacBio Sequel长读长测序和Illumina短读长测序进行测序。该菌株的基因组大小为5,173,343 bp，基因组由一条环状染色体组成，G+C含量为45.07%，共包含4,225个预测编码基因。KEGG和COG功能分析表明，该菌株 P. distasonis（帕氏假单胞菌） 与代谢有关，尤其是氨基酸合成与代谢、脂多糖合成、脂肪酸合成与代谢、脂质转运与代谢等。
Figshare2024-05-14 更新70
Hemodynamic parameters in the left ventricle and in the aorta of sham C57BL/6 mice and of sham C57BL/6 Ldlr −/− Cbs +/− and sham AdCBS treated C57BL/6 Ldlr −/− Cbs +/− mice.
Sham C57BL/6 mice (n = 10) were fed normal chow. Sham C57BL/6 Ldlr−/−Cbs+/− (n = 11) and AdCBS treated (n = 11) C57BL/6 Ldlr−/−Cbs+/− mice were fed with folate-depleted, methionine-enriched diet suppl
NIAID Data Ecosystem50
In vivo base editing extends lifespan of a humanized mouse model of prion disease
Prion disease is a fatal neurodegenerative disease caused by the misfolding of prion protein (PrP) encoded by the PRNP gene. While there is currently no cure for the disease, depleting PrP in the brai
NIAID Data Ecosystem80
Additional file 1: of Reductions in hypothalamic Gfap expression, glial cells and α-tanycytes in lean and hypermetabolic Gnasxl-deficient mice
RNAseq list of gene expression changes in hypothalamus samples from Gnasxl m+/p- mice versus WT littermates. Genes are listed by their log2(fold change) from most up-regulated to most down-regulated.
Figshare2016-12-15 更新60
