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Mesenchymal transition and acquired therapy resistance of glioblastoma cells is connected to astrocyte reactivity (DNA methylation data set)

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NIAID Data Ecosystem2026-03-12 收录
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE122808
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We show that Glioma initiating cells (GICs) can, through MES transition, enter a reactive-astrocyte-like cell state which is connected to increased therapy resistance Illumina Infinium Methylation EPIC array analyses were performed according to the manufacturer's directions on genomic DNA extracted from clonal malignant glioma cells in time series of IL1 stimulation (1-42 days) and corresponding control cells.
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2020-12-03
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