FInnish National Protein Crystallography Consortium

The Finnish BAG encompasses 25 groups active in crystallography in Finland. The projects vary widely and include membrane proteins such as membrane pyrophosphatases, and various protein complexes and receptors (growth factor receptors, integrins), signaling proteins such as kinases, other proteins involved in disease and antibiotics development (neuronal adhesion and myelin proteins, PP2A, ADP-ribosylation and biocatalytic enzymes) and several pathogen proteins (e.g. viral proteins) and various enzyme targets and e.g. studies on phytochrome photoreceptors and complexes involved in actin and cytoskeleton dynamics and regulation. Overall the BAG serves the national needs for highly variable projects, with different biological and biotechnological applications. Several project will benefit from microfocus beam lines and tunable wavelength options for phasing, others benefit from quick robust screening by MASSIF. Biology lab is needed for SAXS experiments.