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Supplementary Table 3 from Activated d16HER2 Homodimers and SRC Kinase Mediate Optimal Efficacy for Trastuzumab

NIAID Data Ecosystem2026-05-26 收录

数据链接：

https://figshare.com/articles/dataset/Supplementary_Table_3_from_Activated_d16HER2_Homodimers_and_SRC_Kinase_Mediate_Optimal_Efficacy_for_Trastuzumab/22403597 数据链接链接失效反馈

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73 genes composing the "activated-d16HER2 signature".

应用场景：

创建时间：

2014-11-01

HER2阳性乳腺癌

药物反应预测

Thirteen HER2 positive breast cancer cell lines were screened with 22 commercially available compounds, mainly targeting proteins in the ErbB2 signaling pathway, and the molecular mechanisms related t

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Gene expression signature overlap between shETV1 and BRD32048 in LNCaP and SK-MEL-28. Homo sapiens

转录因子抑制

基因表达特征分析

Identification of BRD32048 as an inhibitor of ETV1 oncogenic transcription factor. This compound was indentified by small molecule mcroarray (a binding assay). It was able to consistently inhibit an E

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BRD8 is a therapeutic vulnerability for overcoming resistance to dual ER/HER2 blockade therapy in HR+/HER2+ breast cancer

HER2阳性乳腺癌

单细胞RNA测序

.rda file for Seurat object of scRNA-seq data from BT474 breast cancer cell lines treated with DMSO, Neratinib, Fulvestrant, and a combination of Neratinib and Fulvestrant.

Zenodo2023-05-04 更新30

Expression profiling defines a recurrence signature in lung adenocarcinoma

肺腺癌复发预测

基因表达特征分析

Lung cancer remains the leading cause of cancer death worldwide. Overall 5-year survival is about 10-15% and despite curative intent surgery, treatment failure is primarily due to recurrent disease. C

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Design of a gene signature to analyze the proinflammatory and the profibrotic polarization of murine fibroblasts and validation in an experimental murine model of scleroderma.. Design of a gene signature to analyze the proinflammatory and the profibrotic polarization of murine fibroblasts and validation in an experimental murine model of scleroderma.

纤维化疾病

基因表达特征分析

Effect of TGFb1, TNFa, IL6-IL6R, IL1b on gene expression in Mouse Embryonnic Fibrobroblasts (3T3) using RNA microarrays. Overall design: Enrichment analysis of the differentially expressed genes (DEGs

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Supplementary Table 3 from Activated d16HER2 Homodimers and SRC Kinase Mediate Optimal Efficacy for Trastuzumab

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